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General Information

Name Information
Code: T092
Test Name, Short: AFP
A.K.A.: AFP
Matrix: Serum
Turnaround Time: Daily
Analytical Method: two-site sandwich immunoassay
Reportable - Test Results Type: Quantitative
Units - Conventional: ng/mL

Specimen Information

Name Information
Min. Volume: 10 µL
Preferred Volume: 500 µL
Rejection Criteria: Improper labeling, Improper sample handling, Wrong sample type, Outside of stability, Inadequate specimen volume received, or Hemolyzed specimens.
Collection Instructions: See blood collections
Collection Patient Prep: Collect maternal serum specimens for open NTD testing before amniocentesis. Significant quantities of AFP may pass into the maternal circulation during amniocentesis causing MSAFP levels to increase. Since the estimated half-life of AFP in serum is 4 to 6 days,40,41 the MSAFP levels may be falsely elevated.42 Therefore, if serum specimens are not collected before amniocentesis, postponement of MSAFP testing for at least 2 weeks after amniocentesis is recommended. • Treat amniotic fluid specimens contaminated with red blood cells with caution because fetal blood drawn with amniotic fluid may artificially elevate the AFP result. If red blood cell contamination is suspected, then evaluate the amniotic fluid for the presence of fetal hemoglobin. • Centrifuge amniotic fluid specimens to clarify them before testing or freezing. • All amniotic fluid samples can be automatically diluted 1:100 by the system or prepared manually using Multi-Diluent 2.
Container: SST - Collection tube preferred
Shipping Temperature: Ambient